Search results for " TOXICITY"

showing 10 items of 346 documents

Assessment of genetically modified maize 4114 for food and feed uses, under Regulation (EC) No 1829/2003 (application EFSA‐GMO‐NL‐2014‐123)

2018

Abstract Maize 4114 was developed through Agrobacterium tumefaciens‐mediated transformation to provide protection against certain lepidopteran and coleopteran pests by expression of the Cry1F, Cry34Ab1 and Cry35Ab1 proteins derived from Bacillus thuringiensis, and tolerance to the herbicidal active ingredient glufosinate‐ammonium by expression of the PAT protein derived from Streptomyces viridochromogenes. The molecular characterisation data did not identify issues requiring assessment for food/feed safety. None of the compositional, agronomic and phenotypic differences identified between maize 4114 and the non‐genetically modified (GM) comparator(s) required further assessment. There were …

0106 biological sciences4114herbicide toleranceAgrobacteriumCry1F[SDV]Life Sciences [q-bio]Veterinary (miscellaneous)Cry34Ab1Context (language use)4114; Cry1F; Cry34Ab1; Cry35Ab1; GMO; herbicide tolerance; insect-resistant; maize (Zea mays); PAT; Regulation (EC) No 1829/2003TP1-1185Plant Science010501 environmental sciences01 natural sciencesMicrobiologyBacillus thuringiensisinsect‐resistantinsect-resistantTX341-641maize (Zea mays)0105 earth and related environmental sciences2. Zero hungerGenetically modified maizeAnimal healthbiologyNutrition. Foods and food supplyGMObusiness.industryChemical technologyCry35Ab1Regulation (EC) No 1829/2003maize (Zea mays)biology.organism_classificationGenetically modified organismBiotechnologyTransformation (genetics)Scientific Opinion13. Climate actionAnimal Science and ZoologyParasitologybusinessCry 1FPATRegulation (EC) No 1829/2003010606 plant biology & botanyFood SciencePotential toxicity
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Effect of methylparaben in Artemia franciscana.

2017

In this study, the toxicity of methylparaben (MeP) an emerging contaminant, was analysed in the sexual species Artemia franciscana, due to its presence in coastal areas and marine saltworks in the Mediterranean region. The acute toxicity (24 h-LC50) of MeP in nauplii was tested and its chronic effect (9 days) evaluated by measuring survival and growth under two sublethal concentrations (0.0085 and 0.017 mg/L). Also, the effect on several key enzymes involved in: antioxidant defences (catalase (CAT) and gluthathion-S-transferase (GST)), neural activity (cholinesterase (ChE)) and xenobiotic biotransformation (carboxylesterase (CbE), was assessed after 48 h under sublethal exposure. The result…

0106 biological sciencesAntioxidantPhysiologyHealth Toxicology and Mutagenesismedicine.medical_treatmentAquaculture010501 environmental sciencesEndocrine DisruptorsToxicologymedicine.disease_cause01 natural sciencesBiochemistryToxicologyCarboxylesterasechemistry.chemical_compoundMorphogenesisFood scienceToxicity Tests ChronicBiotransformationbiologyMethylparabenArtemia franciscanaGeneral MedicineBiodiversityCatalaseToxicokineticsCatalaseLarvaToxicityParabensArthropod ProteinsLethal Dose 50medicineToxicity Tests AcuteAnimals0105 earth and related environmental sciencesCholinesteraseToxicity010604 marine biology & hydrobiologyPreservatives PharmaceuticalCell BiologySurvival AnalysisAcute toxicityOxidative Stresschemistrybiology.proteinCarcinogensArtemiaXenobioticOxidative stressBiomarkersWater Pollutants ChemicalComparative biochemistry and physiology. Toxicologypharmacology : CBP
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Characteristics of Acute Toxicity Dynamics of Selected Toxicants on Aquatic Crustaceans

2019

Abstract Determining the value of a half-effective or half-life concentration or dose of toxicant is the main purpose of acute toxicity studies, and this is also the most commonly used value in the toxicity characteristics of substances. By conducting tests that meet the criteria and requirements for the determination of acute toxicity, due to the use of appropriate mathematical tools and concentrations resulting in complete lethal effects in the studied groups, considerably more important values can be achieved, which give a possibility for the analysis of the entire process’s dynamics, as well as determining the threshold values of the effect time and toxicant concentration. This was the …

0106 biological sciencesEnvironmental EngineeringbiologyEcologyChemistry010604 marine biology & hydrobiologyEcology (disciplines)010501 environmental sciencesbiology.organism_classification01 natural sciencesCrustaceanAcute toxicityEnvironmental Chemistry0105 earth and related environmental sciencesEcological Chemistry and Engineering S
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Root fungal endophytes: identity, phylogeny and roles in plant tolerance to metal stress.

2021

International audience; Metal trace elements accumulate in soils mainly because of anthropic activities, leading living organisms to develop strategies to handle metal toxicity. Plants often associate with root endophytic fungi, including nonmycorrhizal fungi, and some of these organisms are associated with metal tolerance. The lack of synthetic analyses of plant-endophyte-metal tripartite systems and the scant consideration for taxonomy led to this review aiming (1) to inventory non-mycorrhizal root fungal endophytes described with respect to their taxonomic diversity and (2) to determine the mutualistic roles of these plant-fungus associations under metal stress. More than 1500 species in…

0106 biological sciencesHypocrealesMetal toxicity[SDV.BID.SPT]Life Sciences [q-bio]/Biodiversity/Systematics Phylogenetics and taxonomy01 natural sciencesPlant RootsPlant use of endophytic fungi in defense03 medical and health sciencesAscomycotaPhylogeneticsBotanyGeneticsEndophytesPleosporalesSymbiosisEcology Evolution Behavior and SystematicsPhylogeny030304 developmental biology0303 health sciencesbiologyFungi15. Life on landPlantsbiology.organism_classificationInfectious Diseases[SDE]Environmental SciencesTaxonomy (biology)Metallic trace element Fungal endophytes Taxonomy Accumulation Mutualism Plant-fungi interactions010606 plant biology & botanyFungal biology
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Synergistic reduction of a native key herbivore performance by two non-indigenous invasive algae

2019

Abstract Native generalist grazers can control the populations of non-indigenous invasive algae (NIIA). Here, it was found that the simultaneous consumption of two co-occurring NIIA, Caulerpa cylindracea and C. taxifolia var. distichophylla, hinders the grazing ability of the main Mediterranean herbivorous, the native sea urchin Paracentrotus lividus. The ingestion of any of the two NIIA alone did not produce any difference in sea urchin righting time with respect to usual algal diet. In contrast, the simultaneous consumption of both NIIA, which grow intermingled in nature and are consumed by P. lividus, retarded its righting behavior. Such result reveals substantial physiological stress in…

0106 biological sciencesMediterranean climate010501 environmental sciencesAquatic ScienceOceanographyGeneralist and specialist species01 natural sciencesParacentrotus lividusAlgaeStress Physiologicalbiology.animalGrazingAquatic scienceMediterranean SeaAnimalsCaulerpaHerbivory14. Life underwaterSea urchin0105 earth and related environmental sciencesHerbivorebiologyEcology010604 marine biology & hydrobiologyfood and beveragesbiology.organism_classificationPollutionEnemy release hypothesiBiotic resistance hypothesiParacentrotusSynergistic toxicityIntroduced Species
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Sediment quality assessment using survival and embryo malformation tests in amphipod crustaceans: The Gulf of Riga, Baltic Sea AS case study

2017

Abstract The aim of this study was to assess the toxicity of bottom sediment and to estimate the potential effects of contaminated sediment on health of benthic organisms in the Gulf of Riga (eastern Baltic Sea). Two endpoints were used: survival rate (acute toxicity test) of five crustacean amphipod species and frequency of embryo malformation (samples were collected from the field) in the two species. Toxic resistance of living animals to sediment quality was measured as survival rate (%) at 25 study sites from 2010–2012. Significant differences in the toxic resistance between species were found: 80–100% for Monoporeia affinis, 70–95% for Corophium volutator, 38–88% for Pontogammarus robu…

0106 biological sciencesbiologyEcology010604 marine biology & hydrobiologyHyalella aztecaZoologySediment010501 environmental sciencesAquatic ScienceOceanographybiology.organism_classification01 natural sciencesCrustaceanAcute toxicityBenthic zoneLittoral zoneMonoporeiaCorophium volutatorEcology Evolution Behavior and Systematics0105 earth and related environmental sciencesJournal of Marine Systems
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Differential toxicity of simazine and diuron to Torilis arvensis and Lolium rigidum

1990

Summary: In a soil application, Torilis arvensis was nearly as susceptible as Lolium rigidum to simazine but was 18-fold more tolerant to diuron. Treat ment with diuron inhibited photosynthesis in L. rigidum but had only a limited effect in T. arvensis although chloroplasts isolated from both species displayed similar susceptibility. 14C-diuron degradation in plants was limited, with the formation of conjugates of mono-methyl-diuron in T. arvensis and N-dealkylated derivatives of diuron in L. rigidum. 14C-diuron entered the roots and was translocated throughout the leaves of L. rigidum but was restricted to stems, leaf petioles and leaf veins of T. arvensis. This difference in transport pat…

0106 biological sciencesbiologyved/biologyLolium rigidumved/biology.organism_classification_rank.speciesSimazine04 agricultural and veterinary sciencesPlant Sciencebiology.organism_classification01 natural sciencesDifferential toxicityLoliumchemistry.chemical_compoundchemistryBotany040103 agronomy & agricultureTorilis arvensis0401 agriculture forestry and fisheries[SDV.BV]Life Sciences [q-bio]/Vegetal Biology[SDV.BV] Life Sciences [q-bio]/Vegetal BiologyAgronomy and Crop ScienceEcology Evolution Behavior and SystematicsComputingMilieux_MISCELLANEOUS010606 plant biology & botany
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Essential Oils Extracted from Different Species of the Lamiaceae Plant Family as Prospective Bioagents against Several Detrimental Pests

2020

On the basis of the side effects of detrimental synthetic chemicals, introducing healthy, available, and effective bioagents for pest management is critical. Due to this circumstance, several studies have been conducted that evaluate the pesticidal potency of plant-derived essential oils. This review presents the pesticidal efficiency of essential oils isolated from different genera of the Lamiaceae family including Agastache Gronovius, Hyptis Jacquin, Lavandula L., Lepechinia Willdenow, Mentha L., Melissa L., Ocimum L., Origanum L., Perilla L., Perovskia Kar., Phlomis L., Rosmarinus L., Salvia L., Satureja L., Teucrium L., Thymus L., Zataria Boissier, and Zhumeria Rech. Along with acute to…

0106 biological sciencesfood.ingredientHyptisLavandulaPhytochemicalsPharmaceutical ScienceReviewacute toxicitysublethal effectsSatureja01 natural sciencesRosmarinusessential oilAnalytical Chemistrylaw.inventionTeucriumlcsh:QD241-441foodlcsh:Organic chemistrylawDrug DiscoveryOils Volatilesublethal effectPesticidesPhysical and Theoretical ChemistrymonoterpenoidsEssential oilLamiaceaeMolecular StructurebiologyTraditional medicineOrganic ChemistryOriganumbiology.organism_classification010602 entomologyChemistry (miscellaneous)Insect RepellentsSettore BIO/03 - Botanica Ambientale E ApplicataMolecular MedicineLamiaceae010606 plant biology & botanyMolecules
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Inter- and intraspecific variability in invertebrate acute toxicity response to Arsenic and Fluoride exposure

2018

The adverse effects of arsenic and fluoride exposure on six groups of freshwater invertebrates were investigated. Acute toxicity tests (48-h) with arsenic trioxide (As2NO3) resulted in the following pattern of sensitivity: Daphnia magna 24-h-old = Brachionus patulus 72-h-old = Daphnia. cf. prolata, 21-d-old = D. magna 5-d-old > Heterocypris incongruens juvenile instars > Culex sp. Heterocypris juv. incongruens instars were the second group more tolerant to arsenic and the second group that bioconcentrates arsenic the least. In contrast, invertebrates exposed to sodium fluoride (NaF), showed a different pattern of sensitivity: H. incongruens instars > B. patulus = D. magna 24-h-old > D. cf. …

0301 basic medicine030102 biochemistry & molecular biologyfungiZoologychemistry.chemical_elementBiologyAcute toxicityIntraspecific competition03 medical and health scienceschemistry.chemical_compound030104 developmental biologychemistryZoologiaFluorideInvertebrats d'aigua dolçaArsenicArsènic ToxicologiaInvertebrate
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Synergistic activation of AMPK prevents from polyglutamine-inducedtoxicity inCaenorhabditis elegans

2020

11 páginas, 4 figuras. Supplementary material related to this article can be found, in the online version, at doi: https://doi.org/10.1016/j.phrs.2020.105105.

0301 basic medicineAMPKProtein subunitMutantEnzyme ActivatorsAMP-Activated Protein KinasesProtein Serine-Threonine KinasesProtein Aggregation PathologicalpolyQ toxicityArticleAnimals Genetically ModifiedProtein Aggregates03 medical and health sciences0302 clinical medicineRNA interferenceAutophagymedicineAnimalsAMPK Caenorhabditis elegans Metformin Salycilate Synergy polyQ toxicityCaenorhabditis elegans ProteinsCaenorhabditis elegansLoss functionCaenorhabditis elegansNeuronsPharmacologybiologyChemistrySalycilateAutophagyAMPKDrug Synergismbiology.organism_classificationSalicylatesMetforminCell biologyMetforminEnzyme ActivationSynergy030104 developmental biology030220 oncology & carcinogenesisMutationProteostasisPeptidesmedicine.drug
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